Department of energy classified succinic acid sa as one of the twelve most promising biobased building blocks for the future for good reasons. Chemical conversion pathways to butyrolactone, tetrahydrofuran, 1,4. Although europe dominated the global biobased succinic acid market in 2017, north america is anticipated to become the most profitable venture biobased succinic acid by 2026end. These data exemplify the formulation flexibility of biobased succinic acid and its use as a key building block in polyester polyols for pusespecially for pu coatings. Almost infinite esters can be obtained from carboxylic acids. It is found in small amounts in brown coal, amber, plants, and animals. In supplements, it is used for symptoms related to menopause such as hot flashes and irritability. As a carbonintermediate chemical, fermentationderived succinate has the potential to supply over 2. Bio succinic acid can be used to create chemicals such as 1,4butanediol and. Biobased succinic acid sa is a fourcarbon diacid that is easily produced by direct glucose fermentation using a modified yeast or bacteria. It is not pyrophoric and does not emit flammable gases when it comes into contact with water. I am under impression that it does work as a booster.
For instance petrobased chemical maleic anhydride was the key element for bdo production. Intense competition to drive biobased succinic acid market. Bio basedsuccinic acid is manufactured by the fermentation of sugars, with an aim to replace traditional petroleumbasedsuccinic acid. May 01, 2016 biobased succinic acid sa is a fourcarbon diacid that is easily produced by direct glucose fermentation using a modified yeast or bacteria. Enhanced succinic acid production by mannheimia employing. Bioamber had designed its former commercial plant in sarnia for the production of biobased succinic acid to operate with its yeast technology.
Europe biobased succinic acid market mordor intelligence. Biobased chemicals and polymers opportunities and growth predictions. This statistic outlines the production capacity of the leading biosuccinic acid producers worldwide, as of 2016. Succinic acid is a byproduct of anaerobic fermentation in microbes. Succinic acid, also known as amber acid or butanedioic acid, is a dicarboxylic acid having the molecular formula of c 4 h 6 o 4. Succinic acid production derived from carbohydrates. Uses, side effects, interactions, dosage, and warning. Biosuccinic acid can be used to create chemicals such as 1,4butanediol and. With a large and constantly increasing manufacturer pool, the global biobased succinic acid market is demonstrating a highly competitive business landscape. After its first purification of succinic acid from amber by georgius agricola in 1546, it has been produced by microbial fermentation for the use in agricultural, food and pharmaceutical industries. Bio based succinic acid is primarily preferred for.
The objective was to further the understanding of the process and bring largescale biobased production of succinic acid closer to realisation. Pdf sustainability assessment of succinic acid production. Development of succinic acid producers and f ermentation strategies with an aim to develop costcompetitive bio based sa production processes from renewable nonfood biomass, three impor tant. Biomass derived biooil have been investigated intensively as an alternative of diesel and gasoline fuels.
The organic phase bio oil can be easily upgraded to transport fuel. Succinic acid butanedioic acid is a dicarboxylic acid that occurs naturally in plant and animal tissues. Petrobased chemicals such as maleic anhydride, adipic acid, phthalic anhydride are now being replaced with biobased succinic acid across the application areas. This approach is expected to combine strain development upstream. Biobased succinic acids are of similar structural formulations as that ofconventional petroleumbased succinic acids. Succinic acid is an important industrial chemical that is traditionally derived from petroleum feedstocks. In living organisms, succinic acid takes the form of an anion, succinate, which has multiple biological roles as a metabolic intermediate being converted into fumarate by the enzyme succinate dehydrogenase in complex 2 of the. Bioamber was established in december 2008 as dnp green technology, when the succinic acid assets were spun off from diversified natural products. Petrobased succinic acid is projected to be the largest segment of the market during the forecast period. The product is being increasingly used in a wide range of applications including bdo, pbspbst, and polyester polyols.
When enzymatic hydrolysate of corn stover was used as carbon source. Biooil could be fractionized into organic phase and aqueous phase parts. Succinic acid was dissolved in purified water collected from an ac at a concentration of 2 gl and applied every two weeks by spraying late in the evening. Several relatively largescale biobased succinic acid production plants are currently being built. Succinic acid is predicted to be one of the future platform chemicals that can be derived from renewable resources. North america succinic acid market volume by application, 20122022 kilo tons bioderived succinic acid has the potential to replace butane based maleic anhydride in the manufacturing of a broad spectrum of chemicals such as succinic anhydride, fumaric acid, diethylmaleate, glyoxylic acid, and other plastics.
Overview of the potential of biosuccinic acid production. Petro based succinic acid is projected to be the largest segment of the market during the forecast period. Renewable chemical platforms building the biobased economy. Prior to the advances in yeastcatalyzed molecular engineering, succinic acid was typically obtained from petrochemical sources such as either a benzene oxidationreduction process or more commonly from the partial oxidation of butane.
Five different groups are active in commercial scale capacity development of bio based succinic acid. The succinic acid market is projected to witness a cagr of 22. Following the spin off, the companys shares were distributed to diversified natural products shareholders, making bioamber a standalone legal entity with no ties to diversified natural products. High levels of succinate impairs 2oxoglutarate epigenetic signalling. Malate dehydrogenase mdh is one of the key enzymes for succinic acid sa bioproduction. The global bio succinic acid market size was valued at usd 7. Biotechnology of succinic acid production and markets for. It is used in several areas from highvalue niche applications, such as food and pharmaceuticals, to largevolume applications, such as plasticizers, resins and coatings. The succinic acid building block enables pus with greatly improved solvent and abrasion resistances, and can produce pus with greater stiffness and higher moduli values. Succinic acid is very versatile, it delivers new sustainable options for a wide range of applications in food, cosmetics, pharmaceutical and the chemical, plastic and textile industry. The global biobased succinic acid market is expected to clock a robust cagr of approximately 20. The improvements in biotechnological succinic acid production are presented. Succinic acid has a melting point of 185c and a density of 1.
But the acquisition of some companies by other in general bigger and better. Succinic acid is a dicarboxylic acid that occurs in nature in such organisms as fungi and lichens. Succinic acid, derived from fermentation of agricultural carbohydrates, has a specialty chemical market in industries producing food and pharmaceutical products, surfactants and detergents, green solvents and biodegradable plastics, and ingredients to stimulate animal and plant growth. Handbook of commercial biobased chemicals malonic acid dglucose 1,5pentanediamine pyruvic acid fumaric acid succinic acid some bioroutes to chemical intermediates furan dicarboxylic acid itaconic acid levulinic acid 1,6hexanediol september 2016 prospectus.
Possesses chemical stability as well as incompatibility with bases, oxidizing agents and reducing agents. The demand for petrobased succinic acid is high due to its costeffectiveness and efficiency in various applications in the chemical industry, such as polyester polyols. It is a dicarboxylic acid and an intermediate in kreb. Bioamber commericalizes biobased succinic acid chemistry inspired by nature duration. Bio oil could be fractionized into organic phase and aqueous phase parts. The present work addresses different aspects of succinic acid production by fermentation using metabolically engineered escherichia coli. The failure of bio based succinic acid due to the lack of costcompetitiveness and performance issues as a substitute for petro based succinic acid has increased the demand for petro based succinic acid. The market for the same is estimated to decline by 2019. Several relatively largescale bio based succinic acid production plants are currently being built. Polymorphism in succinate dehydrogenase leads to succinate accumulation. Due to the negative impact of the conventional succinic acid, emphasis is laid on production and consumption of biobased succinic acid.
The companies have been conducting research under a joint development agreement on biobased succinic acid since 2009. The companies have been conducting research under a joint development agreement on bio based succinic acid since 2009. Since early 2008 the two companies have been working together to develop the best and most sustainable fermentative technology to produce biobased succinic acid. Bioambers biobased succinic acid production plant, ontario. The demand for petro based succinic acid is high due to its costeffectiveness and efficiency in various applications in the chemical industry, such as polyester polyols for manufacturing polyurethane, pbs, and personal care.
Culture media are, in most applications, highly speci. The failure of biobased succinic acid due to the lack of costcompetitiveness and performance issues as a substitute for petrobased succinic acid has increased the demand for petrobased succinic acid. Displaces petroleum based feedstock for commercial products reduces lifecycle ghg emissions by 94% compared to petrobased succinic acid transformative technology, demonstrates technical and economic advantages of producing valued biochemicals capable of efficiently utilizing domestically available non food. Metabolic pathways for the production of adipic acid that combine the. It can be used in several areas from highvalue niche applications, such as food, beverages and pharmaceuticals, to largevolume applications, such as plasticizers, resins and coatings. Biobased adipic acid the challenge of developing the production. Development of succinic acid producers and f ermentation strategies with an aim to develop costcompetitive biobased sa production processes from renewable nonfood biomass, three impor tant. Succinic acid is one of the key platform chemicals which can be produced via biotechnology process instead of petrochemical process.
According to a new report by transparency market research tmr, the leading players in this market, including koninklijke dsm n. Biobased succinic acid has replaced butanebased maleic anhydride and has been occupied crucial role in biorefining process. Bioamber had designed its former commercial plant in sarnia for the production of bio based succinic acid to operate with its yeast technology. The world market for succinic acid was approximately 30,000 tonnes in 2009, of which less than. In batch cultures, the final succinic acid concentration of 11. Pdf over the past years, biosuccinic acid from renewable resources has gained. Mar 01, 2016 this statistic outlines the production capacity of the leading bio succinic acid producers worldwide, as of 2016. Biobased succinic acid general, product, process, raw. Dec 05, 2017 although europe dominated the global bio based succinic acid market in 2017, north america is anticipated to become the most profitable venture bio based succinic acid by 2026end. Five different groups are active in commercial scale capacity development of biobased succinic acid. The newly developed process combines high efficiency with the use of renewable substrates and the fixation of the greenhouse gas co2 during the production. The organic phase biooil can be easily upgraded to transport fuel. Succinic acid petroleum and biobased market by source.
Succinic acid is a dicarboxylic acid widely used as acidity regulator in food and beverage. Succinate or succinic acid is involved in several chemical processes in the body. With the presence of 4 gl glucose in the medium, succinic acid concentration increased from 1. Primary products bio succinic acid capacity 30 million pounds per year of bio succinic acid award date march 31, 2010 ghg reduction greater than 60% reduction versus petroleum based product anticipated job creation 50 direct jobs, more than 250 jobs during construction peak, and more than 250 indirect jobs. The global biobased succinic acid market is expected to clock a robust. Biobased succinic acid production avoids the use of this route and instead takes advantage of a process called fermentation. It was primarily used externally for rheumatic aches and pains. When it was first discovered, it was extracted from amber by pulverizing and distilling it using a sand bath. Bio succinic acid market applications and geography size.
Primary products biosuccinic acid capacity 30 million pounds per year of biosuccinic acid award date march 31, 2010 ghg reduction greater than 60% reduction versus petroleumbased product anticipated job creation 50 direct jobs, more than 250 jobs during. As a acidity regulator, succinic acid can be used in a wide variety of industries including. A number of companies are commercializing the production of succinic acid from renewable resources via the fermentation of sugars, with the intent of making biobased succinic acid a dropin replacement for conventional succinic acid. Due to the negative impact of the conventional succinic acid, emphasis is laid on production and consumption of bio based succinic acid. The name derives from latin succinum, meaning amber.
Biobased succinic acid market global analysis, growth. North america succinic acid market volume by application, 20122022 kilo tons bioderived succinic acid has the potential to replace butanebased maleic anhydride in the manufacturing of a broad spectrum of chemicals such as succinic anhydride, fumaric acid. Sa, butanedioic acid is an important chemical, traditionally derived from petroleum feedstocks. Production of succinic acid by bacterial fermentation. Biooil based biorefinery strategy for the production of. Mar 02, 2016 bioamber commericalizes bio based succinic acid chemistry inspired by nature duration. Bio succinic acid is primarily being used as a replacement for petrol based succinic acid in few applications such as solvents and lubricants, deicer solutions, cosmetics, food and pharma. Succinic acid is produced industrially mainly by the hydrogenation of maleic anhydride. Biomass derived bio oil have been investigated intensively as an alternative of diesel and gasoline fuels. Succinic acid article about succinic acid by the free. This will keep the global biobased succinic acid market lucrative. Bioamber had a license from johnson matthey davy technologies a catalyst technology that converts bio based succinic acid into bio based 1,4butanediol bdo. Bio succinic acid market applications and geography. Succinic acid was applied each time at least 2 days after fertilization but i dont recall seeing such effect from just a fertilizer.